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Access denied Category:General, IBComputer security, IBComputers, Business, Documents and Communications, and Information technologies, E-business, and Data transmission, and Networking, Embedded, Espionage, Identity Management, Information security, and Communications, Internet, Internet-related, Malware, Mobile, Mail and Newsgroups, Organizational, Phishing, Protected health information, Public records, Security, Spam, Spam - e-mail, Spying, Theft, Trojan, Trojan horse, Worms, and Web mail, Anti-Virus, and Anti-virus software, Anti-spam, and Anti-spam software, Anti-spyware, and Anti-spyware software, Content filtering, DDoS (Distributed denial-of-service), ESET, Hackers, Malware, Spam, Threat, and Worm, Mass malware, Viruses, Malware and malware, Computer viruses, Malware protection, Antivirus software, Mail filter, Virus protection, Malware protection, Spyware protection, Hacking, Virus protection, Antivirus, and Worm, Microsoft, and Windows operating system, Windows operating system, Windows Operating System, Windows software, Windows, and Computing.Pharmacokinetics and safety of single- and multiple-dose aripiprazole: a randomized, placebo-controlled, double-blind study. Aripiprazole is a novel antipsychotic agent with a novel mode of action. The pharmacokinetic profile of aripiprazole after single and multiple doses was evaluated in a double-blind, placebo-controlled study. Patients with schizophrenia, schizoaffective, or bipolar disorder were randomly assigned to receive a single dose (10 mg or 20 mg) of aripiprazole or placebo. Blood samples for measurement of aripiprazole concentrations were obtained for 24 hours. In a double-blind, crossover study, patients received multiple oral doses of aripiprazole, 10 mg twice daily for 3 days and then 20 mg twice daily for 3 days. Steady-state pharmacokinetics of aripiprazole after multiple dosing were assessed. Forty-two patients (21, 10, and 11 in the single-dose 10-mg, single-dose 20-mg, and multiple-dose 10-mg treatment groups, respectively) were enrolled. Steady-state concentrations of aripiprazole were detectable in plasma for up to 48 hours after





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